| Fri 10/11/17 | West Didsbury & Chorlton v Irlam * | 3-5 | | | | |
| Tue 14/11/17 | West Didsbury & Chorlton v Barnton | 1-4 | |  | | |
| Sat 18/11/17 | 1874 Northwich v West Didsbury & Chorlton | 1-0 | | | | |
| Mon 20/11/17 | Winsford United v West Didsbury & Chorlton | 5-1 | | | | |
| Tue 28/11/17 | West Didsbury & Chorlton v Northwich Victoria | 1-2 | | | | |
| Sat 02/12/17 | Barnoldswick Town v West Didsbury & Chorlton | 4-1 | | | | |
| Tue 12/12/17 | Hyde United v West Didsbury & Chorlton | 5-2 | | | | |
| Sat 16/12/17 | Burscough v West Didsbury & Chorlton | 4-5 | | | | |
| Sat 13/01/18 | West Didsbury & Chorlton v Winsford United | 3-2 | | | | |
| Tue 23/01/18 | West Didsbury & Chorlton v AFC Darwen | 4-1 | | | | |
| Wed 21/02/18 | Runcorn Town v West Didsbury & Chorlton | 3-2 | | | | |
| Sat 24/02/18 | West Didsbury & Chorlton v Abbey Hey | 2-2 | | | | |
| Wed 07/03/18 | AFC Darwen v West Didsbury & Chorlton | 3-3 | | | | |
| Sat 10/03/18 | Squires Gate v West Didsbury & Chorlton | 1-2 | | | | |
| Tue 13/03/18 | West Didsbury & Chorlton v Hanley Town | 3-3 | | | | |
| Sat 17/03/18 | Padiham v West Didsbury & Chorlton | 6-1 | | | | |
| Sat 31/03/18 | Charnock Richard v West Didsbury & Chorlton | 1-2 | | | | |
| Tue 10/04/18 | West Didsbury & Chorlton v Padiham | 3-1 | | | | |
| Thu 12/04/18 | West Didsbury & Chorlton v AFC Liverpool | 1-2 | | | | |
| Sat 14/04/18 | Northwich Victoria v West Didsbury & Chorlton | 1-2 | | | | |
| Tue 17/04/18 | AFC Liverpool v West Didsbury & Chorlton | 3-2 | | | | |
| Sat 21/04/18 | West Didsbury & Chorlton v 1874 Northwich | 2-1 | | | | |
| Sat 28/04/18 | Widnes v West Didsbury & Chorlton | 4-0 | | | | |
| Sat 05/05/18 | West Didsbury & Chorlton v Ashton Athletic | 4-2 | | | | |
