| Sat 04/08/18 | Bootle v Irlam | 0-0 | | | | |
| Sat 11/08/18 | Winsford United v Irlam | 1-2 | | | | |
| Sat 25/08/18 | Prescot Cables v Irlam | 1-2 | | | | |
| Mon 27/08/18 | Irlam v Litherland REMYCA | 2-2 | | | | |
| Sat 08/09/18 | Runcorn Town v Irlam | 2-3 | | | | |
| Tue 11/09/18 | Irlam v Silsden | 3-3 | | | | |
| Sat 15/09/18 | Irlam v Burscough | 4-2 | | | | |
| Sat 22/09/18 | Dunston UTS v Irlam | 2-1 | | | | |
| Tue 25/09/18 | Abbey Hey v Irlam | 2-1 | | | | |
| Sat 29/09/18 | Irlam v Charnock Richard | 2-4 | | | | |
| Sat 06/10/18 | Barnoldswick Town v Irlam | 2-2 | | | | |
| Sat 13/10/18 | Irlam v Handsworth Parramore | 2-0 | | | | |
| Mon 15/10/18 | Winsford United v Irlam | 0-2 | | | | |
| Sat 20/10/18 | Irlam v Abbey Hulton United | 1-3 | | | | |
| Tue 23/10/18 | West Didsbury & Chorlton v Irlam | 0-1 | | | | |
| Sat 27/10/18 | Irlam v Ashton Athletic | 0-0 | | | | |
| Tue 30/10/18 | Squires Gate v Irlam | 2-5 | | | | |
| Sat 03/11/18 | Irlam v Hemsworth Miners Welfare | 3-1 | | | | |
| Sat 10/11/18 | Silsden v Irlam | 2-5 | | | | |
| Sat 17/11/18 | Irlam v Congleton Town | 1-0 | | | | |
| Sat 24/11/18 | Whitchurch Alport v Irlam | 1-1 | | | |  |
| Sat 01/12/18 | Irlam v Winterton Rangers | - | | | | |
| Sat 08/12/18 | Winterton Rangers v Irlam | 0-2 | | | | |
| Sat 15/12/18 | Runcorn Town v Irlam | 1-1 | | | | |
| Sat 22/12/18 | Irlam v Squires Gate | 0-2 | |  | | |
| Wed 26/12/18 | Irlam v Northwich Victoria | 0-4 | | | | |
| Sat 29/12/18 | Irlam v Abbey Hey | 1-2 | | | | |
| Sat 05/01/19 | Irlam v Cadbury Athletic | 4-0 | | | | |
| Sat 12/01/19 | 1874 Northwich v Irlam | 2-4 | | | | |
| Wed 16/01/19 | Litherland REMYCA v Irlam | 5-1 | | | | |
| Sat 26/01/19 | Irlam v Winsford United | 3-1 | | | | |
| Sat 09/02/19 | Irlam v Chertsey Town | 0-2 | | | | |
